The Club was formed in 1928 by Manchester City Director, John Ayrton and the owner of Belle Vue Leisure Park, John Iles. Ayrton created Manchester Central because he felt East Manchester needed a League side. City had moved out of the area in 1923, but had initially considered moving to Belle Vue. The club played at the Belle Vue Athletics stadium, more commonly known as the Speedway Stadium. One of the coaches was Billy Meredith, the Welsh international and former Manchester City and Manchester United player. The manager was James McMahon.
The club joined the Lancashire Combination in its first year finishing seventh in the twenty team competition. This led to an immediate application to join the Football League for the 1929–30 season; this bid failed.